Kamis, 20 Maret 2014

[D702.Ebook] Download Ebook Thermodynamics of Biochemical Reactions, by Robert A. Alberty

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Thermodynamics of Biochemical Reactions, by Robert A. Alberty

Thermodynamics of Biochemical Reactions, by Robert A. Alberty



Thermodynamics of Biochemical Reactions, by Robert A. Alberty

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Thermodynamics of Biochemical Reactions, by Robert A. Alberty

Thermodynamics of Biochemical Reactions emphasizes the fundamental equations of thermodynamics and the application of these equations to systems of biochemical reactions. This emphasis leads to new thermodynamic potentials that provide criteria for spontaneous change and equilibrium under the conditions in a living cell.

  • Sales Rank: #2631148 in Books
  • Published on: 2003-02-27
  • Original language: English
  • Number of items: 1
  • Dimensions: 11.16" h x .98" w x 8.74" l, 2.67 pounds
  • Binding: Hardcover
  • 408 pages

Review
"Through the writing of his new book, Professor Alberty has performed a great service to future textbook authors and to their readers, as well as to the biochemical community in general.” (Biochemistry and Molecular Education, Nov/Dec 2003)

"...a useful learning device...through the writing of his new book, Professor Alberty has performed a great service to future textbook authors and their readers, as well as to the biochemical community in general." (Biochemistry and Molecular Biology Education,Vol. 31, No. 6)

"...this book will prove useful for students and working biochemists...highly recommended..." (Choice, September 2003)

"...emphasizes the application of the fundamental equations of thermodynamics to systems of enzyme-catalyzed reactions making up the metabolism of living organisms." (Pharmaceutical Research, Vol. 20, No. 9, September 2003)

"...written by the most experienced authority in this field...well-written and -organized, and nicely produced..." (Angewandte Chemie International Edition, Vol 42(37), 2003)

"...the authors are to be congratulated on producing an updated, valuable and comprehensive review of the field..." (ChemPhysChem, Vol 5, 2004)

From the Back Cover
An innovative text with a focus on metabolism and enzyme-catalyzed reactions

An excellent teaching text and resource with modern examples and references to the primary literature, Thermodynamics of Biochemical Reactions emphasizes the fundamental equations of thermodynamics and the application of these equations to systems of biochemical reactions. This emphasis leads to new thermodynamic potentials that provide criteria for spontaneous change and equilibrium under the conditions in a living cell.

The theme of the book is that Legendre transforms make the application of thermodynamics more convenient for the users. In Chapter 4, "Thermodynamics of Biochemical Reactions at Specified pH," a Legendre transform is used to introduce pH and pMg as independent intensive variables. In Chapter 6, "Systems of Biochemical Reactions," the steady-state concentrations of various coenzymes are introduced as independent intensive variables in discussing systems of enzyme-catalyzed reactions. In Chapter 8, "Phase Equilibrium in Aqueous Systems," a Legendre transform is used to introduce the electric potential of a phase as an independent intensive variable. Each instance illustrates the author?s belief that the choice of variables, while seemingly an innocuous step, often plays a critical role in formulating a solution. Other chapters include:

  • Chemical Equilibrium in One-Phase Systems
  • Thermodynamics of Binding of Ligands by Proteins
  • Redox Reactions
  • Use of Semigrand Partition Functions

Practicing researchers in pharmaceutical and biotechnical corporations, as well as graduate and upper level undergraduate students in biophysical chemistry or biochemistry, will find Thermodynamics of Biochemical Reactions to be a peerless resource.

About the Author
ROBERT A. ALBERTY, PhD, is Professor Emeritus at the Massachusetts Institute of Technology in Cambridge, Massachusetts. He is also a coauthor of Physical Chemistry, Third Edition (2001), also published by Wiley.

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9 of 10 people found the following review helpful.
Biochemical Thermodynamics--- Clear at Last
By Dr. Daniel L. Purich
While some molecular life scientists may regard biochemical thermodynamics as an esoteric field, and while this book may find its way onto more university library shelves than personal bookshelves, an inescapable fact is that the systematic application of thermodynamic principles is a cornerstone of research in the molecular life sciences. Dr. Alberty's new book provides a lucid and valuable account of biochemical thermodynamics, a field that he has personally advanced through the publication of dozens of peer-reviewed scientific papers for over half a century. His major contribution in recent years has been to extend the concept of isomer group thermodynamics and Legendre transforms for calculations of the Gibbs energy as a function of pH, pMg2+,pO2, etc., an approach that facilitates thermodynamic analysis of complex biochemical reactions. This approach treats interacting molecular species (such as ATP4-, HATP3-, MgATP2-, MgHATP1-, KATP3-, KHATP2-, etc,) as pseudoisomers that rapidly interconvert by their respective association/dissociation reactions. The method also uses matrix algebra to avoid otherwise cumbersome and frequently approximate treatments based on the algebra of multiple equilibria. Enlightened by Alberty's beautifully presented theoretical treatment of isomer group thermodynamics and enabled by his step-by-step guidance (provided in latter half of his book), those seeking a rigorous understanding of bioenergetics can conveniently use the commercially available Mathematica software to perform all required calculations. Two qualities strongly commend the purchase of "Thermodynamics of Biochemical Reactions" for the personal library. First, at its price, the book is a real bargain (kudos to the publisher: John Wiley & Sons). Second, one may be reasonably confident that Alberty's rigorous treatment has now reached a state of timelessness, itself a much appreciated condition for both equilibrium thermodynamics and scientific thought. So, even if you are that biochemist who stubbornly choses not to add this book to her/his personal library, you should at least borrow the library copy to school yourself in modern thermodynamic principles by using what will surely become a classic. One caveat here: Be prepared to stand in line at the book recall desk; this is one book that will rarely be found resting on a library shelf at most research universities.

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[A228.Ebook] PDF Download The Art of Language Invention: From Horse-Lords to Dark Elves, the Words Behind World-Building, by David J. Peterson

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The Art of Language Invention: From Horse-Lords to Dark Elves, the Words Behind World-Building, by David J. Peterson

An insider’s tour through the construction of invented languages from the bestselling author and creator of languages for the HBO series Game of Thrones and the Syfy series Defiance

From master language creator David J. Peterson comes a creative guide to language construction for sci-fi and fantasy fans, writers, game creators, and language lovers. Peterson offers a captivating overview of language creation, covering its history from Tolkien’s creations and Klingon to today’s thriving global community of conlangers. He provides the essential tools necessary for inventing and evolving new languages, using examples from a variety of languages including his own creations, punctuated with references to everything from Star Wars to Michael Jackson. Along the way, behind-the-scenes stories lift the curtain on how he built languages like Dothraki for HBO’s Game of Thrones and Shiväisith for Marvel’s Thor: The Dark World, and an included phrasebook will start fans speaking Peterson’s constructed languages. The Art of Language Invention is an inside look at a fascinating culture and an engaging entry into a flourishing art form—and it might be the most fun you’ll ever have with linguistics.

  • Sales Rank: #17898 in Books
  • Brand: David J Peterson
  • Published on: 2015-09-29
  • Released on: 2015-09-29
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.50" h x .80" w x 5.50" l, 1.00 pounds
  • Binding: Paperback
  • 304 pages
Features
  • The Art of Language Invention From Horse Lords to Dark Elves the Words Behind World Building

Review
“David Peterson's language work transformed our show, investing it with a sense of reality and history that would have been impossible without him. There's nothing like the real thing, and David Peterson is it. This fascinating book will not only illuminate the task of language creation--it will make you look at your own language in a whole new way.”
—David Benioff and D.B. Weiss, co-creators of HBO's Game of Thrones 

“George R. R. Martin created Khal Drogo, and David Benioff and Dan Weiss believed in me, but David Peterson gave me life.”
—Jason Momoa

“David J. Peterson’s The Art of Language Invention accomplishes a minor miracle in taking a potentially arcane discipline and infusing it with life, humor and passion.  It makes a compelling and entertaining case for language creation as visual and aural poetry.  I cherish words, I love books about words and for me this is the best book about language since Stephen Fry’s The Ode Less Traveled.  And, best of all, there’s a phrasebook!”
—Kevin Murphy, co-creator and showrunner of Syfy’s Defiance

“If you want to know how someone makes up a language from the ground up, you'll find out how in this book—and the glory of it is that along the way you'll get the handiest introduction now in existence to what linguistics is. In fact, read this even if you DON'T feel like making up a language!”
—John McWhorter, author of The Language Hoax

“Accessible, entertaining, and thorough, Peterson has created an invaluable resource for authors, dedicated fans, and casual enthusiasts. This is the book I wish I'd had when I started writing.”
—Leigh Bardugo, New York Times bestselling author of Shadow and Bone

“This book not only lucidly ushers language invention into its own as an art form, it's also an excellent introduction to linguistics.”
—Arika Okrent, author of In the Land of Invented Languages
  
"Mr. Peterson illuminates the ins and outs of being a professional developer of “constructed languages”...Language invention requires not only technical know-how but also playfulness and a degree of historical savvy.”
—The Wall Street Journal

About the Author
David J. Peterson began creating languages in 2000, received his MA in Linguistics from the University of California, San Diego, in 2005, and cofounded the Language Creation Society in 2007. He has created languages for HBO’s Game of Thrones, Syfy’s Defiance and Dominion, the CW’s Star-Crossed, and Thor: The Dark World. He is also the author of Living Language Dothraki.

Excerpt. © Reprinted by permission. All rights reserved.

When I was a kid, the original Star Wars trilogy had just completed its initial run in theaters, and Star Wars was everywhere. I had a toy sand skimmer (which I broke), a toy TIE fighter (which I also broke), and a read-along Return of the Jedi picture book with accompanying record which would play the sound of a ship’s blaster when you were supposed to turn the page. (If you’re too young to be familiar with record players as anything other than “vinyl,” type “Pac-Man record read along” into YouTube to familiarize yourself with the concept. That was my childhood.)

In short, aside from He-Man, Star Wars was pretty much the thing if you were a child of four in 1985. At that age, when I watched movies, I didn’t really pay careful attention to the dialogue, and wasn’t able to follow stories that well. Consequently when the Star Wars trilogy was rereleased in 1995, I rewatched it eagerly. Once I got to Return of the Jedi, I was struck by what I thought was a particularly bizarre scene. In the beginning of the movie, Princess Leia, disguised as a bounty hunter, infiltrates Jabba the Hutt’s palace in order to rescue Han Solo. She pretends to have captured Chewbacca, and engages Jabba to negotiate a price for handing him over. In doing so, Leia pretends to speak (or evidently does speak, via some sort of voice modification device) a language Jabba doesn’t. He employs the recently acquired C-3PO as an intermediary. As near as I can tell, this is how the exchange goes (transcription is my own; accent marks indicate where the main stress is):

LEIA: Yaté. Yaté. Yotó. (SUBTITLE: “I have come for the bounty on this Wookiee.”)

C-3PO relays this message and Jabba says he’ll offer 25,000 for Chewie.

LEIA: Yotó. Yotó. (SUBTITLE: “50,000, no less.”)

C-3PO relays this message and Jabba asks why he should pay so much.

LEIA: Eí yóto.

The above isn’t subtitled, but Leia pulls out a bomb and activates it.

C-3PO: Because he’s holding a thermal detonator!

Jabba is impressed by this and offers 35,000.

LEIA: Yató cha.

The above isn’t subtitled, but Leia deactivates the bomb and puts it away.

C-3PO: He agrees.

Order is restored.

I want you to remember that I was in seventh or eighth grade at the time that I was rewatching this. I was not a “language” guy at that point by any stretch of the imagination. I never dreamed that a human could invent a language, and even if I had, I probably wouldn’t have been able to come up with a good reason for one to do so. Furthermore, up to that point, I’d never studied a second language, and the prospect filled me with dread (I had enough trouble understanding my Spanish-speaking relatives who always spoke too fast for me).

But even so, I knew something was wrong here. How on earth does Leia say the same thing twice and have it mean something different the second time? Even if we take C-3PO for an unreliable translator (he is quite loquacious, after all), that applies only to the last two phrases. How could one expect to have an unreliable subtitle? Subtitles are supposed to lie outside the world of the film. If you can’t rely on a subtitle provided by the film’s creators, how can you rely on anything?

In trying to resolve this conflict, it occurred to me that the only plausible explanation for this aberrant phenomenon is that the language itself was correct, but worked differently from all other human languages. In our languages (take English, for example), a word’s meaning can be affected by the context it’s in, but if you control for context, the word will always mean the same thing. Thus, if you’re telling a story about your dog, and you use the word “dog” several times throughout the story, it will still refer to a fur-covered animal that barks and covets nothing so highly as table scraps. This is fairly standard and uncontroversial.

What would happen if a language didn’t do that, though?

Take, for example, the word I have transcribed as yotó above. What if it changed its meaning over the duration of a discourse? Naturally, one would have to define a discourse, but I think it’s fair to consider this conversation featuring Leia, Jabba, and C-3PO a single discourse, so we can leave that concern aside for the moment. What if the word yotó has several definitions? Specifically, what if the first time it’s used in a conversation it means “this wookiee”; the second time it’s used it means “50,000”; and the third time it’s used it means “no less” (or the rough equivalent of those)? The same, then, applies for all other words in the language. That would resolve the ambiguity. How could one possibly use such a language? Well, they are all aliens (Star Wars, recall, takes place a long time ago in a galaxy far, far away). Maybe they’re just better at this stuff than humans. Why not?

This was where my brain went while rewatching Return of the Jedi for the first time. At some future date I may have shared this with a friend, but if I did, the response was likely an eyeroll. This quirk was just an unimportant detail in an otherwise fantastic movie. Why bother about it?

And so that’s pretty much where my thought experiment died. I didn’t take it any further, and no one was really interested, so I didn’t think about it again until college.

But that, of course, was a different era—a pre-internet era. Who does a teenager have to share news with other than their family, friends, and teachers? Who do they come in contact with? In 1995, that’s pretty much only the people who live near you and with whom you interact on a daily basis. How would you ever get ahold of anyone else? How would I have known that someone in the Bay Area, let’s say—less than five hundred miles away—had the same idea I’d had and also found that exchange interesting? In 1995, there was no way.

Then the internet happened.

Yes, the internet had been around for a while in 1995, but it wasn’t a thing that just anyone could have access to. America Online changed all that. Pretty soon it became a thing to race home from school and go into a chatroom with a bunch of random people to talk about . . . nothing. And that was how we entertained ourselves—for hours. What a world, where you could chat with someone who lived in Lancaster, Pennsylvania, about how Soundgarden rules!

As it turns out, though, I wasn’t the only person to pick up on this. Another conlanger I’d later meet at the First Language Creation Conference, Matt Haupt, asked exactly the same question, and devoted a blog post to deconstructing that scene specifically. And we weren’t the only ones. The Ubese language has its own entry on the Wookieepedia (yes, that’s a thing) where contributors have written up an entire backstory for the language that is, first of all, not a full language, and, ultimately, poorly constructed and not worthy of serious consideration.

So let me bring back David Benioff and Dan Weiss’s question to me on the night of the Game of Thrones premiere. If the actors speaking Dothraki or High Valyrian or Castithan or whatever make a mistake, who would know but the creator? Who would care? The truth is probably one in a thousand people will notice, and of those who do, maybe a quarter will care. In the 1980s that amounts to nothing. In the new millennium, though, one quarter of 0.001 percent can constitute a significant minority on Twitter. Or on Tumblr. Or Facebook. Or Reddit. Or on whatever other social media service is currently taking the internet by storm. To take a recent (at the time of writing) example, there was Frozen fan fiction and fan art circulating the internet before the movie had even premiered—and when it did premiere, it took a matter of hours for everyone to learn that Kristoff’s boots weren’t properly fastened, and that this was a big deal as it was disrespectful to the Sami people and their culture.

One of the most significant things about our new interconnected world is that the internet can amplify a minority voice exponentially. Yes, few people, comparatively speaking, will care if an actor makes a mistake with their conlang lines. But thanks to the internet, those few people will find each other, and when they do, they’ll be capable of making a big noise. Every single aspect of every single production on the big and small screen is analyzed and reanalyzed the world over—and in real time. Every level of every production is being held to a higher standard, and audiences are growing savvier by the day. Language—created or otherwise—is no exception. In order to meet the heightened expectations of audiences everywhere, we have to raise the bar for languages created for any purpose. After all, if we don’t, we’ll hear about it.

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3 of 3 people found the following review helpful.
The Art of Language Invention educates and inspires as much as it entertains.
By Daniel M. Bensen
I spent a lot of time waiting in doctors’ offices last week, and I needed something to save me from boredom- and anxiety-induced insanity. What better choice could I have made than The Art of Language Invention by David J. Peterson?

Back when I was a kid, one of my favorite books was Dougal Dixon’s After Man: a Zoology of the Future. As an exercise in speculative biology, the book is responsible for maybe 90% of my enthusiasm about evolution, anatomy, and animal behavior. The fact that I know anything about those subjects at all is because I was enthusiastic for them, which puts Dixon to blame for most of what I know about the natural world. When I read The Art of Language Invention, the same thing happened with linguistics.

You can’t create a good made-up language without knowing about real languages. Through the lens of his invented languages and his experience using them, Peterson educates the reader about the forces that shape the way we speak—a practical gift wrapped in shiny packaging. Like all good speculation, The Art of Language Invention educates and inspires as much as it entertains.

And it IS entertaining, if for no other reason than the cat and onion jokes.

Go read it. I expect to see your new language on my desk by Monday.

5 of 5 people found the following review helpful.
I kind of want to teach an Intro to Linguistics course just so I can use this as the textbook
By BenJamin P. Johnson
If you’ve ever thought about creating a language, but didn’t know where to start, or you were intimidated or overwhelmed by the masses of terminology or “denseness” of other books, start here. If you’ve been creating languages for decades and just need a fresh perspective, a good laugh, or some commiseration, check this out. If you’re a linguistics student struggling with the basics, and your Intro to Linguistics reading is so dry you can’t choke it down, this could easily pass as a funny, entertaining, and fairly complete Linguistics 101 textbook, with some conlanging on the side.

2 of 2 people found the following review helpful.
How to be a conlanger.
By John E. Clifford
David Peterson is a genuinely nice guy, a trained linguist. a good writer and probably the most successful creator of languages today. All of this comes together in his book, which tells how to create a realistic language with copious examples from how Peterson actually did create Dothraki and the half dozen or so other languages now playing on your screen, large or small. While there is enough technical material to satisfy most conlanger needs, it is always wrapped in practical applications to make it palatable. The main theme is to grow your created language as much like a natural one as possible, starting in the past and working toward your target. As a result, most of standard linguistics finds their places along with a lot of less systematic advice -- the way things typically go, even if there is no rule about it. And each section is illustrated with an inside look at how its content applied in one of Peterson's languages, for the added buzz that may bring.

Now, I am an engelanger myself, with only minor excursions into artlangs of the sort that Peterson is describing, so I feel somewhat left out. But only somewhat, for Peterson's discussion of linguistics and the way languages actually work have great value for more outre' languages -- as something to NOT do, if nothing else, but mainly as a guide to a unified creation that might be learnable and speakable, while still performing some experimental task. Auxlangers, seeking an international auxiliary language, will be less left out, since they do look for some sort of naturalness along with universal appeal. And it is quite clear that Petersons's languages, however many people learn them to talk to khaleesi, are meant for their own cultures, not for ours.

If you are bitten by the desire to create a language, this is the easiest path to satisfying that urge> You may want to go to other works later, but this gives you the foundation and the direction you will need.

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Rabu, 19 Maret 2014

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Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi

Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi



Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi

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Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi

Trust the proven “Four Box” method to formulate ethically appropriate recommendations for patient care

Clinical Ethics teaches healthcare providers how to effectively identify, evaluate, and resolve ethical issues in clinical medicine. Using the author acclaimed “Four Box Method” and numerous illustrative case examples, this book enables practitioners to gain a better understanding of the complexities involved in ethical cases and demonstrates how to reach resolution to ethical problems.

Clinical Ethics goes beyond theory to offer a decision-making strategy applicable to real-world practice. Readers will learn an easy-to-apply system based on simple questions about medical indications, patient preferences, quality of life, and contextual features that clearly explain clinical ethics and help them formulate a sound diagnosis and treatment strategy. The case examples have been selected to demonstrate how principles apply to real-world everyday practice.

The co-authors, a bioethicist, a physician and a lawyer/ psychoanalyst /philosopher, draw on more than forty years respectively of clinical experience to select exemplary cases of ethical problems and to reflect on how moral principles and concepts can guide clinicians in formulating ethically appropriate recommendations for patient care.

A unique chapter organization:
Each chapter of the book begins with some general considerations about the topic, and the ethical principle relevant to that topic. The clinical situations that generate ethical problems are then described and illustrated by clinically realistic medical cases. A short distillation of current opinion from the bioethical literature is provided, followed by an analysis of the cases.. The authors conclude with recommendations that the three authors have formulated from their extensive experience as bioethics consultants.


  • Sales Rank: #60396 in Books
  • Brand: McGraw-Hill Professional
  • Published on: 2015-06-30
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.90" h x .70" w x 5.80" l, .70 pounds
  • Binding: Paperback
  • 256 pages

About the Author

Albert Jonsen, Ph.D. is affiliated with the University of California San Francisco School of Medicine.
Mark Siegler, M.D. is affiliated with the University of Chicago.
William Winslade, Ph.D., J.D. is affiliated with University of Texas Medical.

Most helpful customer reviews

25 of 25 people found the following review helpful.
This is an excellent resource for those in medical settings.
By A Customer
The authors suggest another method of evaluating ethical dilemmas. They suggest one examine the situation in light of medical indications, patient preferences, quality of life, and contextual features.

Because the approach is clinical, rather than theoretical, some of the medical details presented are somewhat technical. This is a book for those working in a medical setting or otherwise engaged with medical ethics.

I read the book based on the recommendation of a bioethics lecturer. It was further recommended recently by the Director of the Program in Medical Ethics for University of California, Irvine.

--Mary Kay Buike, MSW, ACSW;
Oncology Social Worker and member of a hospital
Bioethics Committee

20 of 21 people found the following review helpful.
Concise, yet comprehensive sytematic approach to bioethics
By Robert Henderson
Dr. Jonsen is one the nation's germinal thinkers in the field of bioethics. Through his experience and associations at several of the renowned medical academic institutions in this coutnry he sets forth a clear systematic approach to problems in bioethics. This includes a review of his "4-box" method for approaching ethical problems and then reviews basic ethical principles as well as legal definitions. His approach to clincal dilemmas provides a refreshing analytical process for dilineating issues and conflicts.

3 of 3 people found the following review helpful.
Clinical Ethics
By DCR
Good presentation of the principles of clinical ethics with examples of many dilemmas and thoughtful analysis of case presentations.
Very readable. Succinct. Useful. Particularly helpful for people new to the field. Highly recommended

See all 16 customer reviews...

Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi PDF
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Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi PDF
Clinical Ethics, 8th Edition: A Practical Approach to Ethical Decisions in Clinical Medicine, 8E, by Albert R. Jonsen, Mark Siegler, Willi PDF

Kamis, 13 Maret 2014

[C618.Ebook] Download Ebook Design for Manufacturability: How to Use Concurrent Engineering to Rapidly Develop Low-Cost, High-Quality Products for Lean ProductionBy

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Design for Manufacturability: How to Use Concurrent Engineering to Rapidly Develop Low-Cost, High-Quality Products for Lean ProductionBy

Design for Manufacturability: How to Use Concurrent Engineering to Rapidly Develop Low-Cost, High-Quality Products for Lean Production shows how to use concurrent engineering teams to design products for all aspects of manufacturing with the lowest cost, the highest quality, and the quickest time to stable production. Extending the concepts of design for manufacturability to�an advanced product development model, the book explains how to simultaneously make major improvements in all these product development goals, while enabling effective implementation of Lean Production and quality programs.

Illustrating how to make the most of lessons learned from previous projects, the book proposes numerous improvements to current product development practices, education, and management. It outlines effective procedures to standardize parts and materials, save time and money with off-the-shelf parts, and implement a standardization program. It also spells out how to work with the purchasing department early on to select parts and materials that maximize quality and availability while minimizing part lead-times and ensuring desired functionality.

  • Describes how to design families of products for Lean Production, build-to-order, and mass customization
  • Emphasizes the importance of quantifying all product and overhead costs and then provides easy ways to quantify total cost
  • Details dozens of design guidelines for product design, including assembly, fastening, test, repair, and maintenance
  • Presents numerous design guidelines for designing parts for manufacturability
  • Shows how to design in quality and reliability with many quality guidelines and sections on mistake-proofing (poka-yoke)

Describing how to design parts for optimal manufacturability and compatibility with factory processes, the book provides a big picture perspective that emphasizes designing for the lowest total cost and time to stable production. After reading this book you will understand how to reduce total costs, ramp up quickly to volume production without delays or extra cost, and be able to scale up production rapidly so as not to limit growth.

  • Sales Rank: #365003 in Books
  • Published on: 2014-02-04
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.30" h x 1.10" w x 6.20" l, .0 pounds
  • Binding: Hardcover
  • 486 pages

About the Author

Dr. David M. Anderson, P.E.,�is the world’s leading expert on using concurrent engineering to design products for manufacturability. Over the past 27 years presenting customized in-house DFM seminars, he has honed these methodologies into an effective way to accelerate the real time-to-stable-production and significantly reduce total cost.

His book-length website, www.HalfCostProducts.com, presents a comprehensive cost reduction strategy�consisting of eight strategies. DFM is a key half-cost strategy because it supports most of the others. Dr. Anderson shows clients how to apply these strategies for cost reduction, ranging from half cost to an order of magnitude, which he teaches in customized in-house seminars, workshops, and design studies to generate innovative breakthrough concepts.

In the management of technology program at the University of California at Berkeley, he wrote and taught the product development course twice. He wrote the opening chapter in the sixth volume of the SME Tool and Manufacturing Engineers Handbook. His second book on mass customization, Build-to-Order & Mass Customization: The Ultimate Supply Chain Management and Lean Manufacturing Strategy for Low-Cost On-Demand Production Without Forecasts or Inventory, is described in Appendix D.

Dr. Anderson has more than 35 years of industrial experience in design and manufacturing. For seven years, his company, Anderson Automation, Inc., built special production equipment and tooling for IBM and OCLI and did design studies for FMC, Clorox Manufacturing, and SRI International. As the ultimate concurrent engineering experience, he personally built the equipment he designed in his own machine shop. He has been issued four patents and is working on more.

Dr. Anderson is a fellow of ASME (American Society of Mechanical Engineers) and a life member in SME (Society of Manufacturing Engineers). He is a certified management consultant (CMC) through the Institute of Management Consultants. His credentials include�professional registrations in mechanical, industrial, and manufacturing engineering and a doctorate in mechanical engineering from the University of California, Berkeley, with a major in design for production and minors in industrial engineering, metalworking, and business administration.

Dr. Anderson can be reached via email: anderson@build-to-order-consulting.com. His websites are www.design4manufacturability.com and www.HalfCostProducts.com.

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Minggu, 09 Maret 2014

[H930.Ebook] Download PDF 5 Very Good Reasons to Punch a Dolphin in the Mouth (And Other Useful Guides)

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5 Very Good Reasons to Punch a Dolphin in the Mouth (And Other Useful Guides)

  • Sales Rank: #5218847 in Books
  • Published on: 1900
  • Binding: Paperback

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Senin, 03 Maret 2014

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  • Sales Rank: #132247 in Books
  • Brand: Brand: Oxford University Press
  • Published on: 2011-10-10
  • Original language: English
  • Number of items: 1
  • Dimensions: 4.40" h x .40" w x 6.70" l, .26 pounds
  • Binding: Paperback
  • 152 pages
Features
  • Used Book in Good Condition

Review

"This quite brilliant 'introductory essay' has as its main point that the specificity of French collective identity and culture is - and has always been - in its ability to blend a very strong sense of national self with universalist values. Everyone who wants to know more about modern French culture and history should read this book." -Patrice Higonnet, Robert Walton Goelet Professor of French History, Harvard University


"How could anyone boil down modern France to, what, 30,000 words? It's impossible, of course. To approach the subject in the space of two journal articles, you'd have to make a series of strategic choices, settle on an angle of attack, discard strict chronology, and focus on what interests you the most. Vanessa Schwartz did all these things and more in this gem of an essay on modern France, a book that will be useful and enjoyable to specialists and general readers alike."--H-France Review


About the Author

Vanessa Schwartz is Professor of History at the University of Southern California and author of It's SO French! Hollywood, Paris and the Making of Cosmopolitan Film Culture.

Most helpful customer reviews

17 of 17 people found the following review helpful.
Very New (2011) Into to Modern France
By Ray
If someone were to ask me to write a summary of modern France that was only about 140 moderate-to-small sized pages, I'm not sure how I would handle the task. I've spent enough time in France and read enough books about the country and its history that I would probably spend as much time just trying to select topics as I would actually writing. The history of France itself is an incredibly detailed and interesting one, but how would I describe modern France itself in such a short space? I fear I would not be able to, easily becoming caught up in all the topics, themes, currents, events, and movements that have added up to making France what it is today.

So, when I saw a new book that purports to summarize Modern France in such a format, I was a tiny bit skeptical. Interested, but skeptical. The advantage of short, summarized works, of course, is that the author does the hard work of slicing out, selecting, and summarizing from vast swaths of source material to develop something that is easily digestible. The drawback, also of course, is that such summaries rarely can convey "essence" without throwing away all the details that are essential components of that very essence." But, to my delight, Vanessa Schwartz has done a very good job with this challenging task in her new book, which is part of Oxford's already truly outstanding "Very Short Introduction" series.

Schwartz's book, though a delight for anyone interested in France, is also very well suited for those new to the topic and wishing to be introduced to this fascinating country. The book provides an introductory framework that uses the French Revolution as both its starting point and an orienting guidepost for all things Franco-Modern, and then quickly (and really quickly, due to the length constraints) hits on the high points of the modern state. We read of movements (the communards, consumerism, etc.), the role of the French language in France and around the world, as well as modern realities (the TGV, the Concord jet, tourism, etc.) as part of this story. And although there is little time to dwell on any of these things, Schwartz has done a great job of weaving much divergent, yet nevertheless, intertwined content into a highly readable narrative that is accessible to nearly anyone. It's as enjoyable to read as it is impressive for its coverage.

I could easily see this book used as a supplemental text for someone studying French and wishing to get a broader understanding of France today. It could also be used by someone planning their first trip to France, and wanting to understand the country just a bit more before the trip (yet it must be said that France is a country that probably needs to be understood from the inside out, as much as the outside in). But it can also be used by anyone with an interest in France and who just wishes to see a new author cut a curve of prose through this fascinating country. The book's readability, pocketability, and content coverage make it not only an excellent addition to the wonderful Oxford series of "A Very Short Introduction", but as a work in its own right. Five stars.

Also See:
For the opposite type of book, where the detail is rich, thick, and extended, see Pierre Nora's highly acclaimed three-volume set in English (translated):
Realms of Memory: Rethinking the French Past, Vol. 1 - Conflicts and Divisions
Realms of Memory: Rethinking the French Past, Vol. 2 - Traditions
Realms of Memory: Rethinking the French Past, Vol. 3 - Symbols

For a truly fascinating and unusual text about the development of modern France, I highly recommend:
The Discovery of France: A Historical Geography

For some other excellent books in 'A Very Short Introduction to ..." that I've enjoyed:
The French Revolution: A Very Short Introduction (Very Short Introductions)
Descartes: A Very Short Introduction (Very Short Introductions)

8 of 8 people found the following review helpful.
Very short - and quite brilliant
By Jon Wiener
Vanessa Schwartz has written a wonderful book about the glories of Paris, of French art and French film, and about the French obsession with their language. The chapter on the French Revoution, which was the beginning of everything, is especially strong -- and her treatment of France's conflicts and contradictions today is sober and smart. It's a great example of how a "very short" book can also be (in the words of Patrice Higgonet) "quite brilliant."

0 of 1 people found the following review helpful.
Not a book reivew
By Kenneth H. Winn
This once contained some information about the vendor service and has nothing to say about the content of this book. Sorry.

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Sabtu, 01 Maret 2014

[K152.Ebook] Free Ebook Sense of Place (Thomas Elkin Book 3), by N.R. Walker

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Sense of Place (Thomas Elkin Book 3), by N.R. Walker

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Sense of Place (Thomas Elkin Book 3), by N.R. Walker

Sense of Place by N.R. Walker

Book three in the Thomas Elkin series

Designing homes is easy. Finding home is something else entirely.

Thomas Elkin and Cooper Jones finally have the support of their families, and their love grows stronger every day. Now living together, they think nothing can stand in their way.

But there are outside influences trying to pull them apart.

Cooper encounters a man, closer to his age and with connections high up the property development chain, who wants Cooper as his own. Tom encounters discrimination and a hidden agenda from a fellow senior partner who’s trying to take him down.

No matter what the world throws at them, Tom and Cooper are the real deal. Age differences aside, Tom has finally found his sense of place. His one true center, his home.


The Thomas Elkin series

A successful New York architect, forty-four year old Thomas Elkin almost has it all. An esteemed traditional draftsman, he thought he knew everything about architecture, about life.

Cooper Jones, twenty-two years old, is about to take the architect world by storm. Talented, professional, driven, and completely infuriating, Cooper is the definition of Generation Y.

Generation versus generation, traditional versus contemporary, these men are about to learn a lesson in architecture, egos and love. Can they prove to the world that the old and new can be the perfect design?


About N.R. Walker

N.R. Walker is an Australian author, who loves her genre of gay romance. She loves writing and spends far too much time doing it, but wouldn't have it any other way.

She is many things; a mother, a wife, a sister, a writer. She has pretty, pretty boys who live in her head, who don't let her sleep at night unless she gives them life with words.

She likes it when they do dirty, dirty things...but likes it even more when they fall in love.

She used to think having people in her head talking to her was weird, until one day she happened across other writers who told her it was normal.

She's been writing ever since...

  • Sales Rank: #238949 in eBooks
  • Published on: 2015-08-17
  • Released on: 2015-08-17
  • Format: Kindle eBook

Most helpful customer reviews

7 of 7 people found the following review helpful.
Perfect Finish
By JustJen
I have been a big fan of this series from pretty much the get go. Each time I start one, I find myself giving a great big sigh of happiness as everything I love about these characters comes rushing back in the first few pages. This installment was no different. I absolutely love Tom and Cooper together and have never had much of an issue with their age difference. They share amazing chemistry and fabulous dialog. Tom is super sexy and sweet, and Cooper is such a character – funny, sexy and sweet all wrapped in one. Their relationship is still going strong and seems to be moving forward with little difficulty, though they are dealing with the added pressure of work and family issues.

Speaking of work issues, Tom has a few to deal with, just as Cooper picks up a contract requiring long hours and dedication. Having been in Cooper’s shoes, Tom is ever the understanding partner. Trouble comes by way of Cooper’s client, who puts the pressure on Cooper to be more than professional. There is a bit of tension surrounding this, and Tom and Coop deal with it the same way they have everything else, with Tom making unintentional mistakes, and Coop waiting him out for him to do things properly. This is one of the things I love about these guys, and they do it consistently throughout this book, as well as the rest of the series.

So, if you’ve read this far, you must love Tom and Coop, as I do. I thoroughly enjoyed this installment and savored every chapter, knowing it was nearing the end of their story. This series has been such an enjoyable and entertaining read, and I’m just not ready to say goodbye. I sure hope we get to see some snippets from them in the future. I highly recommend this for anyone looking for a sexy, sweet, funny, feel-good story.

5 of 5 people found the following review helpful.
Great ending for the series!
By Lisa FFC
If you've read the first two books this is the perfect ending and you HAVE to get it! The banter between Tom & Cooper is better than in the first two. No surprise this authors characters are funny and quick witted because she is too. Honestly, I can't remember when I've smiled so much!

The first two books I've talked about how Tom is my type but I was in love with Cooper. Well, I still adore him (you'd have to be stupid not to) but Tom made me swoon. Everything about him is perfect IMO. He's even tempered, SO good to Cooper and good to Coopers family. He takes off work unexpectedly to help out, even though he's got trouble at work. And sexy, Jesus......

I don't want to give anything away but the end of this is probably the best ever for the characters, for what it is. I smiled, cried and swooned all at the same time. I could easily see another book but sadly, I have it on good authority that this is the end for Tom & Cooper.

If you haven't read this series, you're missing out!

1 of 1 people found the following review helpful.
A delightful ending to a great series
By Jacque
I hate when a good series ends but if has to end, then Sense of Place was the perfect ending to a most enjoyable read.

Tom and Cooper are happily living together now and working out the kinks of couplehood. Unlike the previous titles there's a bit more drama in this one with characters that make you want to hit something, or someone, HARD! Cooper is working on a huge project that is about to make his career...provided a over-inflated ego doesn't get popped first. Cooper isn't the only one with drama within work. Tom's is more personal but oh how I loved that outcome!

Why must all good things come to an end? I could have happily kept reading about Tom and Cooper, as the experience all live has to offer them and they progress through life. I guess I need to be satisfied with knowing Tom finally asks Cooper the RIGHT way *Sigh* and the Epilogue *SIGH!!!* Ms. Walker has quite the series here and it needs to be read by every M/M romance reader. Heck, traditional M/F readers should be reading it, too. Two better characters and their story I have yet to encounter.

I received this book from the JeepDiva for the express purposes of an honest review. The opinions and rating of this review are solely mine and in no way was I compensated.
Stars - 5, Flames - 3

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